Welcome to the Biochemistry Web Page

 

 

Textbook website: Berg, Tymoczko, Stryer (2002)  Biochemistry, WH Freeman


Lecture Topics (chapter)
Lab Activities 		Relevant Links

Week 1
8/26 – 8/30

Introduction, Biochemical Evolution (1,2)
pre-test, intro to online resources		 Hammerhead Ribozyme Structure
NCBI HomePage

Week 2
9/2 – 9/6

Protein Structure (3,7)
Protein structure and sequence analysis with Chime/Protein Explorer.		 Protein Explorer FrontDoor
Biochemistry in 3D - Lehninger
Index of klothopdb - small molecule pdb's

Week 3
9/9 – 9/13

Enzyme Kinetics (8)
Exam 1 (9/13)
Begin integrated informatics project (computer lab)		 Biochemical Nomenclature Committees

Week 4
9/16 – 9/20

Catalytic strategies (9)
Measurement of phosphatase activity		  

Week 5
9/23 – 9/27

Regulation of Enzymes (10)
Phosphatase kinetic analysis

Week 6
9/30 – 10/4

Lipids & Membranes (12, 13)
Exam 2 (10/4)
Phosphatase purification – Part 1 		 

Week 7
10/7 – 10/11

Signal Transduction (15)
Phosphatase purification – Part 2

Week 8
10/14 – 10/16
(long weekend)

Basic metabolic concepts (14)
long weekend – no lab		 ExPASy - Biochemical Pathways

Week 9
10/21 – 10/25

Carbohydrates & their metabolism (11, 16, 21)
Phosphatase Lab report due
Electron Transport Inhibitors		  

Week 10
10/28 – 11/1

Respiration (17, 18)
Exam 3 (11/1)
Purification of a 6xHis-tagged protein		  

Week 11
11/4 – 11/8

Photosynthesis (19, 20)
SDS-PAGE analysis of protein fractions		  

Week 12
11/11 – 11/15

Lipid Metabolism  (22, 26)
TLC analysis of membrane lipids

Week 13
11/18 – 11/22

Amino Acid Metabolism (23-24)
Analysis of Tryptophan auxotrophs

Week 14
12/2 – 12/6

Nucleotide Metabolism, Integration (25, 30)
Analysis of Tryptophan auxotrophs